You're not treating one but two conditions. Firstly, the fever bouts. Second, the amyloid deposits.

What to do during a fever bout

Assuming your Shar Pei is part of the 25% affected by the condition and has been diagnosed by a qualified Veterinarian, the fevers will come and go. The following is a mix of what I learned on my own, from the community and advice from veterinarians.

Confirm the hock's size

It's often unclear if the hock is "swollen" because of the wrinkly nature of Shar Pei. I strongly recommend taking a measurement of the "normal" hock circumference. A simple trick is to wrap your index and thumb around the area and get an idea of the size. When a Shar Pei develops a bout of FSF, it will be considerably larger, by approximately 2 to 3cm (0.7874" to 1.181") or more. Extreme cases can break the skin.

Take their temperature

Shar Peis aren't known to be the most approachable dogs, even by their owners. So it may or may not be possible to take their temperature. In Pillow's case, even though he was quite the little nipper, I managed by waiting for him to be sleepy. I then distracted him with his favorite treat, using a rectal, flexible (rubber) thermometer rubbed in vaseline warmed up with my hands. It did the trick.

Alleviate discomfort

Significant fevers (above 41.1°C / 106°F) can be treated with non-steroidal anti-inflammatory drugs such as Carprofen (commercial names: Rimadyl®, Zinecarp®, Canidryl®, Aventicarp®, Rycarfa®, Rimifin®, Carpox®, Tergive®, Carprodyl®, Carprieve®, Norocarp®) provided by your veterinary at the correct dosage based on the dog's weight.

What to do after the first fever bout

Administer the correct medicine

The above will only alleviate discomfort and confirm the existence of the disorder. Remember, the real danger is the kidney's amyloid deposits. For this, the generally accepted treatment is colchicine once the fever bout has ended. Colchicine is not a temporary treatment - it's for life, the second your Shar Pei has been diagnosed.

Some dogs do not tolerate the side effects of colchicine, so it's not uncommon to see corticosteroids (such as prednisone) being used in its place. They also have side effects.

The use of either colchicine or corticosteroids is often the subject of long arguments at home from well-meaning owners-turned-overnight-google-experts with different views and education on the topic. We have included a section on taking care of yourself as part of this site. We strongly encourage you not to overlook it, especially as things can and will get complicated.

Counter the side effects

If your dog supports colchicine, it's also essential to provide the correct anti-antioxidants, minerals and vitamin supplements as part of a well-balanced diet. We won't go into the details as it could fill a book, but a low-protein diet is a good start. Forget 'sausage treats'.

We can also recommend a product called HyVitality. It is currently available only in the United States of America (using reshippers such as Shipito can solve this problem for international owners). Note that we have absolutely no connection to this company or their product. If you know alternatives, please let us know via email so we can include them.

Miracle cures? No. But does it help to provide supplements and open a recipe book and continue with the low-protein kibble: certainly.